“Treatment of side effects associated with antineoplastic therapy is the indication for cannabinoids which has been most documented, with about 40 studies (THC, nabilone, other THC analogues, marijuana). Most trials were conducted in the 1980s. THC has to be dosed relatively highly, so that resultant side effects may occur comparatively frequently. THC was inferior to high-dose metoclopramide in one study. There are no comparisons of THC to the modern serotonin antagonists. Whereas, dronabinol has a diminished acceptance in the treatment of side effects of chemotherapy, in folk medicine cannabinoids remain popular and are often used in other causes of nausea including AIDS and hepatitis.”
The fist antitumour antibiotic to be clinically evaluated was actinomycin. Since then various other antitumour antibiotics have been used including actinomycin D, bleomycin, daunorubicin, epirubicin, doxorubicin, and mitomycin.